Male Carriers of BRCA1/BRCA2 alterations
Male Breast Cancer Awareness
Because of the increased risk of male breast cancer, particularly with BRCA2 alterations, men with BRCA alterations are advised to pay attention to any changes in the texture of their breast tissue, and to contact their GP if they notice any lumps or changes in the skin on the chest.
Prostate Cancer Risk Management
PSA (Prostate Specific Antigen) is a protein that is often produced by cancers of the prostate. Blood levels of PSA are often increased in men with Prostate Cancer. However, blood levels of PSA can also be increased for a number of reasons other than cancer.
The goal of screening is to detect Prostate Cancer at the earliest possible stage, when cure is most likely, but if screening gives false positive results, this can cause undue anxiety and unnecessary investigations in healthy men.
Research is ongoing to determine if prostate cancer screening using a PSA blood test with or without further investigations is useful in men over the age of 40 at increased risk of Prostate Cancer. Further information about the international IMPACT study, co-ordinated by researchers in the Royal Marsden NHS Trust and Institute of Cancer Research, London, is available here.